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Tumour heterogeneity, the major cause of therapeutic resistance to anti-tumour agents, results from the genetic, epigenetic and microenvironmental selective pressure that tumour cells undergo during cancer progression.The hardest part of the job was trying to fulfill everything that was expected in a day.The most enjoyable part was the people and their many cultures.Pros A culture that enables you to be what you want to be and go as far as your skills/ambition can take you.GE has given me diverse experiences across the globe, in multiple businesses and industries.